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ZNRF1 anticorps

ZNRF1 Reactivité: Humain, Souris, Rat IF (p), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386945
  • Antigène Voir toutes ZNRF1 Anticorps
    ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))
    Reactivité
    • 45
    • 26
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 40
    • 4
    • 1
    Lapin
    Clonalité
    • 43
    • 2
    Polyclonal
    Conjugué
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ZNRF1 est non-conjugé
    Application
    • 25
    • 17
    • 12
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ZNRF1
    Isotype
    IgG
    Top Product
    Discover our top product ZNRF1 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))
    Autre désignation
    ZNRF1 (ZNRF1 Produits)
    Synonymes
    anticorps NIN283, anticorps B830022L21Rik, anticorps Rnf42, anticorps Zrfp1, anticorps nin283, anticorps zgc:77896, anticorps zrfp1, anticorps zinc and ring finger 1, anticorps zinc and ring finger 1, E3 ubiquitin protein ligase S homeolog, anticorps ZNRF1, anticorps Znrf1, anticorps znrf1, anticorps znrf1.S
    Sujet

    Synonyms: E3 ubiquitin protein ligase ZNRF1, E3 ubiquitin-protein ligase ZNRF1, Nerve injury gene 283, Nerve injury induced gene 283 protein, Nerve injury-induced gene 283 protein, NIN283, Rnf42, Zinc and ring finger 1, zinc and ring finger protein 1, zinc finger and ring finger protein 1, Zinc/RING finger protein 1, ZNRF 1, znrf1, ZNRF1_HUMAN, Zrfp1.

    Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. ZNRF1 (zinc and ring finger 1), also known as NIN283, is a 227 amino acid protein that contains one RING-type zinc finger and localizes to the lysosome and the endosome, as well as to cytoplasmic vesicles and the peripheral membrane. Expressed primarily in nervous system tissue, but also present in testis and thymus, ZNRF1 functions as an E3 ubiquitin-protein ligase that is thought to play a role in the establishment and maintenance of neuronal plasticity. Multiple isoforms of ZNRF1 exist due to alternative splicing events.

    ID gène
    84937
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