MARCH8 anticorps

N° du produit ABIN1387037

Détail du produit anti-MARCH8 anticorps

Antigène: MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARCH8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MARCH8

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MARCH8

Antigène: MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))

Autre désignation: MARCH8 (MARCH8 Produits)

Synonymes: anticorps MARCH-VIII, anticorps MIR, anticorps RNF178, anticorps c-MIR, anticorps zgc:171495, anticorps 1300017E09Rik, anticorps Mir, anticorps Mar-08, anticorps MARCH8, anticorps membrane associated ring-CH-type finger 8, anticorps membrane-associated ring finger (C3HC4) 8, anticorps membrane associated ring-CH-type finger 8 L homeolog, anticorps MARCH8, anticorps march8, anticorps March8, anticorps march8.L

Sujet:

Synonyms: c MIR, c-MIR, Cellular modulator of immune recognition, E3 ubiquitin protein ligase MARCH8, E3 ubiquitin-protein ligase MARCH8, MARCH 8, MARCH VIII, MARCH-VIII, MARCH8, MARH8_HUMAN, Membrane associated RING CH protein VIII, Membrane associated ring finger C3HC4 8, Membrane associated RING finger protein 8, Membrane-associated RING finger protein 8, Membrane-associated RING-CH protein VIII, MIR, RING finger protein 178, RNF178.

Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. MARCH8 (membrane-associated ring finger (C3HC4) 8), also known as MIR or RNF178 (RING finger protein 178), is a 291 amino acid multi-pass membrane protein that localizes to vesicle membranes and contains one RING-CH-type zinc finger. Expressed in a variety of tissues, including immature dendritic cells, MARCH8 functions as an E3 ubiquitin ligase that is thought to regulate immune responses by promoting the ubiquitination and subsequent degradation of target proteins, such as B7-2 and CD71.

ID gène: 220972