TMIGD1 anticorps (AA 160-200)

N° du produit ABIN1387070

Détail du produit anti-TMIGD1 anticorps

Antigène: TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))

Épitope: AA 160-200

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMIGD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TMIGD1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TMIGD1

Antigène: TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))

Autre désignation: TMIGD1 (TMIGD1 Produits)

Synonymes: anticorps RGD1307444, anticorps Tmigd, anticorps TMIGD, anticorps UNQ9372, anticorps 2010002A20Rik, anticorps transmembrane and immunoglobulin domain containing 1, anticorps Tmigd1, anticorps TMIGD1

Sujet:

Synonyms: TMIGD, UNQ9372, Transmembrane and immunoglobulin domain-containing protein 1, TMIGD1, UNQ9372/PRO34164

Background: Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dub? syndrome and Canavan disease are also associated with chromosome 17.

ID gène: 388364

UniProt: Q6UXZ0