TRIM8 anticorps

N° du produit ABIN1387072

Détail du produit anti-TRIM8 anticorps

Antigène: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TRIM8/RNF27

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TRIM8

Antigène: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Autre désignation: RNF27 (TRIM8 Produits)

Synonymes: anticorps GERP, anticorps RNF27, anticorps AA408830, anticorps BB006755, anticorps Rnf27, anticorps si:ch211-208d15.5, anticorps wu:fc90g07, anticorps tripartite motif containing 8, anticorps tripartite motif containing 8 L homeolog, anticorps tripartite motif-containing 8, anticorps tripartite motif containing 8b, anticorps TRIM8, anticorps trim8.L, anticorps Trim8, anticorps trim8b

Sujet:

Synonyms: Lioblastoma expressed ring finger protein, Ring finger protein 27, RNF27, RP11-47A8.4, TRIM8, Tripartite mot containing 8, Tripartite mot protein TRIM8, TRIM8_HUMAN.

Background: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM8 (tripartite motif containing 8), also known as GERP (glioblastoma-expressed RING finger protein) or RNF27 (RING finger protein 27), is a 551 amino acid protein that is thought to function as an E3 ubiquitin-protein ligase that promotes SOCS-1 proteasomal degradation. As a widely expressed homodimer, TRIM8 localizes to nuclear bodies and contains two B box-type zinc fingers and one RING-type zinc finger. TRIM8 is expressed in lung, heart, brain and skeletal muscle, with low levels detected in intestine, placenta, leukocytes and liver. The gene encoding TRIM8 maps to human chromosome 10q24.32.

ID gène: 81603

UniProt: Q9BZR9