PDE4A anticorps

N° du produit ABIN1387127

Détail du produit anti-PDE4A anticorps

Antigène: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE4A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PDE4A8

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PDE4A

Antigène: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Abstract: PDE4A Produits

Synonymes: anticorps pde4, anticorps dpde2, anticorps pde46, anticorps PDE4A, anticorps Pde4a, anticorps D9Ertd60e, anticorps Dpde2, anticorps DPDE2, anticorps PDE4, anticorps PDE46, anticorps PHOSA, anticorps phosphodiesterase 4A S homeolog, anticorps phosphodiesterase 4A, cAMP-specific, anticorps phosphodiesterase 4A, anticorps phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila), anticorps cAMP-specific 3',5'-cyclic phosphodiesterase 4A, anticorps phosphodiesterase 4A, cAMP specific, anticorps phosphodiesterase 4C, anticorps pde4a.S, anticorps pde4a, anticorps PDE4A, anticorps LOC100009247, anticorps Pde4a, anticorps PDE4C

Sujet:

Synonyms: 2EL, DPDE2, PDE4, PDE46, PDE4A, Phosphodiesterase 4A, Phosphodiesterse Type 4A8, PDE4A_HUMAN.

Background: The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterized 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialized functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.

ID gène: 5141

Pathways: cAMP Metabolic Process