HELT anticorps (AA 156-220)

N° du produit ABIN1387384

Détail du produit anti-HELT anticorps

Antigène: HELT (Helt BHLH Transcription Factor (HELT))

Épitope: AA 156-220

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HELT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HELT

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur HELT

Antigène: HELT (Helt BHLH Transcription Factor (HELT))

Autre désignation: HELT (HELT Produits)

Synonymes: anticorps HCM1228, anticorps HESL, anticorps Mgn, anticorps bHLHb44, anticorps A830086M02, anticorps Hesl, anticorps megane, anticorps Helt-ps1, anticorps RGD1564073, anticorps zgc:109704, anticorps helt bHLH transcription factor, anticorps HELT, anticorps Helt, anticorps helt

Sujet:

Synonyms: Hairy and enhancer of split-related protein HELT, HCM1228, HELT, HELT_HUMAN, HES like , HES/HEY like transcription factor, HES/HEY-like transcription factor, HESL, Heslike , Hey like transcription factor, Hey like transcription factor zebrafish, Hey like transcriptional repressor, Megane bHLH factor, Mgn.

Background: The Drosophila hairy and Enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis. The Notch signaling pathway is thought to maintain stem cells through transcriptional activation of HES/HEY family members to repress tissue-specific transcription factors. HESL (HES-like), also known as Mgn or HELT (HES/HEY-like transcription factor), is a 327 amino acid nuclear protein belonging to the HEY family. Containing a basic helix-loop-helix (bHLH) domain and an Orange domain, HESL self-associates and interacts with HES5 and HRT2. HESL is considered a transcriptional repressor that binds to the canonical E box sequence 5'-CACGCG-3'. HESL exists as two isoforms produced by alternative splicing events.

Pathways: Feeding Behaviour