RPE65 anticorps

N° du produit ABIN1387436

Détail du produit anti-RPE65 anticorps

Antigène: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPE65 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RPE65

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RPE65

Antigène: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Autre désignation: RPE65 (RPE65 Produits)

Synonymes: anticorps LCA2, anticorps RP20, anticorps mRPE65, anticorps rd12, anticorps sRPE65, anticorps 65kDa, anticorps A930029L06Rik, anticorps Mord1, anticorps DRPE65, anticorps RPE65, anticorps anon-WO0148162.1, anticorps anon-WO0148163.1, anticorps beta-diox, anticorps DmelCG9347, anticorps CG9347, anticorps MGC52887, anticorps MGC154296, anticorps MGC85437, anticorps rpe65, anticorps RPE56c, anticorps si:ch211-198n5.12, anticorps 13cIMH, anticorps RPE56b, anticorps rpepb, anticorps si:ch211-198n5.5, anticorps wu:fc74c09, anticorps zgc:110538, anticorps RPE56a, anticorps rpepa, anticorps zgc:73213, anticorps RPE65, retinoid isomerohydrolase, anticorps retinal pigment epithelium 65, anticorps neither inactivation nor afterpotential B, anticorps retinal pigment epithelium-specific protein 65kDa S homeolog, anticorps retinal pigment epithelium-specific protein 65kDa L homeolog, anticorps RPE65 homolog, anticorps retinal pigment epithelium-specific protein 65kDa, anticorps retinal pigment epithelium-specific protein 65c, anticorps retinal pigment epithelium-specific protein 65b, anticorps retinal pigment epithelium-specific protein 65a, anticorps RPE65, anticorps Rpe65, anticorps ninaB, anticorps rpe65.S, anticorps rpe65.L, anticorps rpe65, anticorps rpe65c, anticorps rpe65b, anticorps rpe65a

Sujet:

Synonyms: All-trans-retinyl-palmitate hydrolase, LCA 2, LCA2, Leber congenital amaurosis, mRPE 65, mRPE65, p63, rd 12, rd12, Retinal pigment epithelium specic 61 kDa protein, Retinal pigment epithelium specic 65 kDa protein, Retinal pigment epithelium specic protein, Retinal pigment epithelium specic protein 65 kDa, Retinal pigment epithelium-specic 65 kDa protein, Retinitis pigmentosa 20, Retinoid isomerohydrolase, RP 20, RP20, RPE 65, RPE65, RPE65_HUMAN, sRPE 65, sRPE65.

Background: The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the _-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.