CTH anticorps

N° du produit ABIN1387469

Détail du produit anti-CTH anticorps

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTH est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Cystathionine gamma lyase

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CTH (ABIN1387469)

Shiina, Shima, Horii, Naitou, Nakamori, Sano, Shimizu: "Inhibitory action of hydrogen sulfide on esophageal striated muscle motility in rats." dans: European journal of pharmacology, Vol. 771, pp. 123-9, (2016) (PubMed).

Détails sur CTH

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Autre désignation: CTH (CTH Produits)

Synonymes: anticorps DYT17, anticorps DYT18, anticorps DYT9, anticorps EIG12, anticorps GLUT, anticorps GLUT1, anticorps GLUT1DS, anticorps HTLVR, anticorps PED, anticorps wu:fb48e03, anticorps wu:fb58d08, anticorps zgc:66001, anticorps zgc:85785, anticorps CTH, anticorps 0610010I13Rik, anticorps AI314617, anticorps BC019483, anticorps CSE, anticorps Cys3, anticorps cysA, anticorps SCQ11.03c, anticorps DDBDRAFT_0190313, anticorps DDBDRAFT_0191318, anticorps DDB_0190313, anticorps DDB_0191318, anticorps H, anticorps MGC75946, anticorps cystathionine gamma-lyase, anticorps solute carrier family 2 member 1, anticorps cystathionase (cystathionine gamma-lyase), anticorps cystathionine gamma-lyase L homeolog, anticorps CTH, anticorps SLC2A1, anticorps cth, anticorps Cth, anticorps SCO3920, anticorps mlr1566, anticorps TA_RS00415, anticorps MAP_RS15640, anticorps SPO3344, anticorps CNN01730, anticorps Mmcs_1928, anticorps RHA1_RS31820, anticorps HNE_1212, anticorps MAV_3867, anticorps MSMEG_2394, anticorps Mvan_2142, anticorps SACE_6136, anticorps Mflv_4220, anticorps cysA, anticorps cth.L

Sujet:

Synonyms: CGL_HUMAN, CTH, Cystathionine gamma lyase, Cystathionine gamma-lyase, Cysteine desulfhydrase, Gamma cystathionase, Gamma-cystathionase, Homoserine deaminase, Homoserine dehydratase, MGC9471, CSE, Cystathionase.

Background: Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.Defects in CTH are the cause of cystathioninuria (CSTNU). It is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine, leading to increased urinary excretion.

ID gène: 1491

Pathways: ER-Nucleus Signaling, L'effet Warburg