THO Complex 2 anticorps (AA 101-200)

N° du produit ABIN1387530

Détail du produit anti-THO Complex 2 anticorps

Antigène: THO Complex 2 (THOC2)

Épitope: AA 101-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp THO Complex 2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human THOC2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur THO Complex 2

Antigène: THO Complex 2 (THOC2)

Autre désignation: THOC2 (THOC2 Produits)

Synonymes: anticorps RGD1561623, anticorps THO, anticorps Tho2, anticorps fb73e08, anticorps fd21d11, anticorps wu:fb73e08, anticorps wu:fd21d11, anticorps si:bz1o18.2, anticorps CXorf3, anticorps THO2, anticorps dJ506G2.1, anticorps hTREX120, anticorps 6330441O12Rik, anticorps D130005M13Rik, anticorps Gm1139, anticorps Gm1793, anticorps THO complex 2, anticorps Thoc2, anticorps THOC2, anticorps thoc2

Sujet:

Synonyms: THO2, CXorf3, hTREX120, dJ506G2.1, THO complex subunit 2, THOC2

Background: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim.

ID gène: 57187

UniProt: Q8NI27