Sulfiredoxin 1 anticorps (AA 45-137)

N° du produit ABIN1387599

Détail du produit anti-Sulfiredoxin 1 anticorps

Antigène: Sulfiredoxin 1 (SRX1)

Épitope: AA 45-137

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sulfiredoxin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SRXN1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Sulfiredoxin 1 (ABIN1387599)

Zhang, He, Guo, Li, Wang, Yang, Cui: "Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways." dans: Bioscience reports, Vol. 36, Issue 2, (2016) (PubMed).

Zhou, Zhou, Yu, Wu, Chen, Zhao et al.: "Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen ..." dans: International journal of molecular medicine, Vol. 36, Issue 1, pp. 43-52, (2015) (PubMed).

Détails sur Sulfiredoxin 1

Antigène: Sulfiredoxin 1 (SRX1)

Autre désignation: SRXN1 (SRX1 Produits)

Synonymes: anticorps C20orf139, anticorps Npn3, anticorps SRX, anticorps SRX1, anticorps Ab2-390, anticorps 1700127B04Rik, anticorps AI854065, anticorps AW488194, anticorps Srx, anticorps Srx1, anticorps TX01, anticorps sulfiredoxin 1, anticorps sulfiredoxin 1 homolog (S. cerevisiae), anticorps SRXN1, anticorps srxn1, anticorps Srxn1

Sujet:

Synonyms: SRX, Npn3, SRX1, C20orf139, Sulfiredoxin-1, SRXN1

Background: Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.

ID gène: 140809

UniProt: Q9BYN0