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TTC21B anticorps (AA 1221-1316)

TTC21B Reactivité: Rat IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1387658
  • Antigène Voir toutes TTC21B Anticorps
    TTC21B (Tetratricopeptide Repeat Domain 21B (TTC21B))
    Épitope
    AA 1221-1316
    Reactivité
    • 14
    • 1
    • 1
    Rat
    Hôte
    • 15
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TTC21B est non-conjugé
    Application
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human TTC21B
    Isotype
    IgG
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TTC21B (Tetratricopeptide Repeat Domain 21B (TTC21B))
    Autre désignation
    TTC21B (TTC21B Produits)
    Synonymes
    anticorps 2410066K11Rik, anticorps Thm1, anticorps aln, anticorps mKIAA1992, anticorps RGD1565122, anticorps ATD4, anticorps IFT139, anticorps JBTS11, anticorps NPHP12, anticorps THM1, anticorps sb:cb947, anticorps tetratricopeptide repeat domain 21B, anticorps Ttc21b, anticorps TTC21B, anticorps ttc21b
    Sujet

    Synonyms: ATD4, JBTS11, Nbla10696, NPHP12, Putative protein product of Nbla10696, Tetratricopeptide repeat protein 21B, THM1, TPR repeat protein 21B, TT21B_HUMAN, Ttc21b.

    Background: The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TTC21B (tetratricopeptide repeat domain 21B), also known as THM1, is a 1,316 amino acid protein that contains 19 TPR repeats and belongs to the TTC21 family. Localizing to cytoplasm and cytoskeleton, TTC21B exists as two alternatively spliced isoforms and is thought to negatively regulate Shh signal transduction. TTC21B may also be involved in retrograde intraflagellar transport in cilia, and is encoded by a gene that maps to human chromosome 2q24.3.

    ID gène
    79809
    UniProt
    Q7Z4L5
    Pathways
    Signalisation Hedgehog
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