CHRND anticorps (AA 145-190)

N° du produit ABIN1387797

Détail du produit anti-CHRND anticorps

Antigène: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Épitope: AA 145-190

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRND est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CHRND

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CHRND

Antigène: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Autre désignation: CHRND (CHRND Produits)

Synonymes: anticorps ACHRD, anticorps CMS2A, anticorps FCCMS, anticorps SCCMS, anticorps wu:fa01e01, anticorps zgc:110469, anticorps CHNRD, anticorps MGC97613, anticorps Achr-4, anticorps Acrd, anticorps L10076, anticorps chnrd, anticorps chrng, anticorps cholinergic receptor nicotinic delta subunit, anticorps cholinergic receptor, nicotinic, delta (muscle), anticorps cholinergic receptor, nicotinic, delta, anticorps cholinergic receptor nicotinic gamma subunit, anticorps cholinergic receptor, nicotinic delta, anticorps cholinergic receptor, nicotinic, delta polypeptide, anticorps cholinergic receptor, nicotinic delta L homeolog, anticorps CHRND, anticorps chrnd, anticorps CHRNG, anticorps Chrnd, anticorps chrnd.L

Sujet:

Synonyms: Acetylcholine receptor delta subunit, Acetylcholine receptor subunit delta, ACHD_HUMAN, ACHRD, Cholinergic receptor, nicotinic, delta polypeptide, CHRND, CMS2A, FCCMS, Nicotinic acetylcholine receptor delta polypeptide precursor, SCCMS.

Background: Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChR delta, also known as CMS2A, FCCMS, SCCMS or CHRND, is a 517 amino acid multi-pass membrane protein that is associated with lethal type multiple pterygium syndrome, congenital myasthenic syndrome slow-channel type (SCCMS) and congenital myasthenic syndrome fast-channel type (FCCMS).