C2orf40 anticorps

N° du produit ABIN1387821

Détail du produit anti-C2orf40 anticorps

Antigène: C2orf40 (Chromosome 2 Open Reading Frame 40 (C2orf40))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C2orf40 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ECRG4/C2orf40

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur C2orf40

Antigène: C2orf40 (Chromosome 2 Open Reading Frame 40 (C2orf40))

Autre désignation: ECRG4 (C2orf40 Produits)

Synonymes: anticorps ECRG4, anticorps ecrg4, anticorps ecrg4-A, anticorps Ecrg4, anticorps chromosome 2 open reading frame, human C2orf40, anticorps chromosome 13 open reading frame, human C2orf40, anticorps chromosome 11 open reading frame, human C2orf40, anticorps chromosome 2 open reading frame 40, anticorps chromosome 2 open reading frame 40 L homeolog, anticorps RIKEN cDNA 1500015O10 gene, anticorps similar to RIKEN cDNA 1500015O10, anticorps C2H2orf40, anticorps C13H2orf40, anticorps C11H2orf40, anticorps C2orf40, anticorps c2orf40.L, anticorps 1500015O10Rik, anticorps RGD1305645

Sujet:

Synonyms: AUGN_HUMAN, Augurin, C2orf40, Esophageal cancer-related gene 4 protein.

Background: ECRG4, also known as augurin or C2orf40, is a 148 amino acid secreted protein. Belonging to the augurin family, ECRG4 is thought to be a hormone. It has also been suggested that ECRG4 may act as a tumor suppressor. The gene that encodes ECRG4 maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes, making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes.

ID gène: 84417