LGR6 anticorps (AA 401-500)

N° du produit ABIN1387842

Détail du produit anti-LGR6 anticorps

Antigène: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Épitope: AA 401-500

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGR6 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Réactivité croisée: Humain, Souris

Homologie: Rat,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LGR6

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur LGR6

Antigène: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Autre désignation: LGR6 (LGR6 Produits)

Synonymes: anticorps LGR6, anticorps GPCR, anticorps VTS20631, anticorps A530037C04Rik, anticorps D830026M09, anticorps RGD1560339, anticorps leucine rich repeat containing G protein-coupled receptor 6, anticorps leucine-rich repeat-containing G protein-coupled receptor 6, anticorps LGR6, anticorps Lgr6

Sujet:

Synonyms: GPCR, VTS20631, Leucine-rich repeat-containing G-protein coupled receptor 6, LGR6, UNQ6427/PRO213

Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.

ID gène: 59352

UniProt: Q9HBX8