PSMD6 anticorps

N° du produit ABIN1387855

Détail du produit anti-PSMD6 anticorps

Antigène: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMD6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PSMD6/Proteasome regulatory particle subunit p44S10

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PSMD6

Antigène: PSMD6 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 6 (PSMD6))

Autre désignation: PSMD6 (PSMD6 Produits)

Synonymes: anticorps Rpn7, anticorps S10, anticorps SGA-113M, anticorps p42A, anticorps p44S10, anticorps DDBDRAFT_0190867, anticorps DDBDRAFT_0232985, anticorps DDB_0190867, anticorps DDB_0232985, anticorps 2400006A19Rik, anticorps P44s10, anticorps zgc:56471, anticorps p44s10, anticorps rpn7, anticorps s10, anticorps 141231_at, anticorps CG5378, anticorps Dmel\\CG5378, anticorps S10a, anticorps anon-WO0172774.103, anticorps anon-WO0172774.106, anticorps proteasome 26S subunit, non-ATPase 6, anticorps 26S proteasome non-ATPase regulatory subunit 6, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 6, anticorps proteasome 26S subunit, non-ATPase 6 S homeolog, anticorps Regulatory particle non-ATPase 7, anticorps PSMD6, anticorps psmD6, anticorps Psmd6, anticorps psmd6, anticorps psmd6.S, anticorps Rpn7, anticorps rpn-7

Sujet:

Synonyms: 26S proteasome non-ATPase regulatory subunit 6, 26S proteasome regulatory subunit RPN7, 26S proteasome regulatory subunit S10, Breast cancer-associated protein SGA-113M, KIAA0107, p42A, P44S10, PFAAP4, PSMD6_HUMAN, Phosphonoformate immuno-associated protein 4, Proteasome prosome, macropain 26S subunit, non-ATPase, 6, Proteasome regulatory particle subunit p44S10, Rpn7, S10 antibody SGA-113M.

Background: In eukaryotic cells, selective breakdown of cellular proteins is ensured by two distinct pathways, ubiquitination and degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome are formed by developmentally regulated alternative splicing, including Rpn10a through Rpn10e (also designated pUb-R2 through pUb-R5). The pUb-R2 subunit, originally identified as S5a, is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells. p44S10 is a highly conserved proteasome regulatory subunit that is expressed in heart, liver, skeletal muscle and pancreas. In addition to normal tissue expression, p44S10 is also expressed in several melanoma cell lines, such as MCF-7, 451Lu and WM164. Since forced expression of p44S10 in radial growth phase melanoma cells results in an increase in cellular proliferation, p44S10 may represent a potential link between regulation of proteasome activity and tumor cell proliferation in vivo.

ID gène: 9861

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway