CHMP2B anticorps (AA 31-120)

N° du produit ABIN1387885

Détail du produit anti-CHMP2B anticorps

Antigène: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Épitope: AA 31-120

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP2B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CHMP2B

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CHMP2B

Antigène: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Autre désignation: CHMP2B (CHMP2B Produits)

Synonymes: anticorps ALS17, anticorps CHMP2.5, anticorps DMT1, anticorps VPS2-2, anticorps VPS2B, anticorps 1190006E07Rik, anticorps RGD1306781, anticorps chmp2b, anticorps chmp2bl, anticorps zgc:77025, anticorps si:ch211-224m9.5, anticorps CHMP2B, anticorps cg4618, anticorps chmp2.5, anticorps dmt1, anticorps vps2-2, anticorps vps2b, anticorps CHMP2b-B, anticorps chmp2b-a, anticorps chmp2b-b, anticorps charged multivesicular body protein 2B, anticorps charged multivesicular body protein 2Bb, anticorps charged multivesicular body protein 2Ba, anticorps charged multivesicular body protein 2B pseudogene, anticorps charged multivesicular body protein 2B S homeolog, anticorps charged multivesicular body protein 2B L homeolog, anticorps CHMP2B, anticorps Chmp2b, anticorps chmp2bb, anticorps chmp2ba, anticorps LOC747711, anticorps chmp2b.S, anticorps chmp2b.L

Sujet:

Synonyms: Charged multivesicular body protein 2b, CHM2B_HUMAN, CHMP2.5, CHMP2b, Chromatin modying protein 2b, Chromatin-modying protein 2b, DMT1, hVps2-2, Vacuolar protein sorting 2-2, VPS2 homolog B, Vacuolar protein sorting-associated protein 2-2, Vps2-2, VPS2B.

Background: The charged multivesicular body proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).