SYNM anticorps (AA 501-650)

N° du produit ABIN1387897

Détail du produit anti-SYNM anticorps

Antigène: SYNM (Synemin, Intermediate Filament Protein (SYNM))

Épitope: AA 501-650

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYNM est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Desmuslin

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SYNM (ABIN1387897)

Bengoechea, Pittman, Tuck, True, Weihl: "Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D." dans: Human molecular genetics, Vol. 24, Issue 23, pp. 6588-602, (2015) (PubMed).

Détails sur SYNM

Antigène: SYNM (Synemin, Intermediate Filament Protein (SYNM))

Autre désignation: Desmuslin (SYNM Produits)

Synonymes: anticorps DMN, anticorps dmn, anticorps si:dkey-25f3.3, anticorps SYN, anticorps 4930412K21Rik, anticorps AI852401, anticorps Dmn, anticorps E130104F11, anticorps Syn, anticorps Synemin, anticorps synemin, anticorps synemin, intermediate filament protein, anticorps SYNM, anticorps synm, anticorps Synm

Sujet:

Synonyms: DMN, SYN, Synemin, Desmuslin, SYNM, KIAA0353

Background: Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.

ID gène: 23336

UniProt: O15061