Transportin 1 anticorps

N° du produit ABIN1387906

Détail du produit anti-Transportin 1 anticorps

Antigène: Transportin 1 (TNPO1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transportin 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Transportin 1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Transportin 1

Antigène: Transportin 1 (TNPO1)

Autre désignation: Transportin 1 (TNPO1 Produits)

Synonymes: anticorps IPO2, anticorps KPNB2, anticorps MIP, anticorps MIP1, anticorps TRN, anticorps TNPO1, anticorps AU021749, anticorps D13Ertd688e, anticorps Kpnb2, anticorps ATTRN1, anticorps F12A24.13, anticorps F12A24_13, anticorps TRANSPORTIN 1, anticorps transportin 1, anticorps DKFZp469O204, anticorps transportin 1, anticorps transportin-1, anticorps transportin 1 S homeolog, anticorps TNPO1, anticorps LOC738932, anticorps tnpo1, anticorps Tnpo1, anticorps tnpo1.S, anticorps TRN1

Sujet:

Synonyms: Importin 2, Importin beta 2, IPO 2, IPO2, Karyopherin importin beta 2, Karyopherin beta 2, KPN B2, KPNB 2, KPNB2, M9 interacting protein, M9 region interacting protein, M9 region interaction protein, M9-interacting protein, MIP 1, MIP, MIP1, TNPO 1, TNPO1, Transportin 1, Transportin, Transportin-1, Transportin1, TRN, TNPO1_HUMAN.

Background: Transportin 1 is the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. In cases of HIV-1 infections, transportin 1 is known to bind and mediate the nuclear import of HIV-1 Rev.

ID gène: 3842

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events