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HEXDC anticorps (AA 1-100)

HEXDC Reactivité: Humain WB, IF (cc), IF (p), IHC (fro), IHC (p), ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1388018
  • Antigène Voir toutes HEXDC Anticorps
    HEXDC (Hexosaminidase D (HEXDC))
    Épitope
    • 14
    • 2
    • 1
    • 1
    AA 1-100
    Reactivité
    • 19
    • 1
    • 1
    Humain
    Hôte
    • 17
    • 2
    Lapin
    Clonalité
    • 19
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HEXDC est non-conjugé
    Application
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human HEXDC
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    HEXDC (Hexosaminidase D (HEXDC))
    Autre désignation
    HEXDC (HEXDC Produits)
    Synonymes
    anticorps BC069960, anticorps fj33c04, anticorps wu:fj33c04, anticorps zgc:152869, anticorps hexdc, anticorps hexosaminidase D, anticorps hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing, anticorps hexosaminidase D L homeolog, anticorps HEXDC, anticorps Hexdc, anticorps hexdc, anticorps hexdc.L
    Sujet

    Synonyms: Beta hexosaminidase D, Beta N acetylhexosaminidase, FLJ23825, Hexosaminidase glycosyl hydrolase family 20 catalytic domain containing, hexosaminidase glycosyl hydrolase family 20, catalytic domain, Hexosaminidase D, Hexosaminidase domain containing protein, N acetyl beta galactosaminidase, HEXDC_HUMAN.

    Background: HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    ID gène
    284004
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