Transferrin Receptor anticorps (AA 621-720) (AbBy Fluor® 555)
-
- Antigène Voir toutes Transferrin Receptor (TFRC) Anticorps
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
-
Épitope
- AA 621-720
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp Transferrin Receptor est conjugé à/à la AbBy Fluor® 555
-
Application
- Flow Cytometry (FACS), Western Blotting (WB)
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Dog,Cow,Pig,Horse,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Transferrin receptor
- Isotype
- IgG
- Top Product
- Discover our top product TFRC Anticorps primaire
-
-
- Indications d'application
- FCM 1:20-100
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- Autre désignation
- Transferrin receptor (TFRC Produits)
- Synonymes
- anticorps Trfr, anticorps LOC100219280, anticorps tfr, anticorps cd71, anticorps tfr1, anticorps trfr, anticorps CD71, anticorps T9, anticorps TFR, anticorps TFR1, anticorps TR, anticorps TRFR, anticorps p90, anticorps 2610028K12Rik, anticorps AI195355, anticorps AI426448, anticorps AU015758, anticorps E430033M20Rik, anticorps Mtvr-1, anticorps Mtvr1, anticorps transferrin receptor, anticorps TFRC, anticorps Tfrc, anticorps tfrc
- Sujet
-
Synonyms: T9, TR, TFR, p90, CD71, TFR1, TRFR, Transferrin receptor protein 1, TFRC
Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
- ID gène
- 7037
- UniProt
- P02786
- Pathways
- Transition Metal Ion Homeostasis
-