STXBP6 anticorps (AA 1-100) (Biotin)

N° du produit ABIN1388911

Détail du produit anti-STXBP6 anticorps (Biotin)

Antigène: STXBP6 (Syntaxin Binding Protein 6 (Amisyn) (STXBP6))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STXBP6 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Amisyn

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur STXBP6

Antigène: STXBP6 (Syntaxin Binding Protein 6 (Amisyn) (STXBP6))

Autre désignation: Amisyn (STXBP6 Produits)

Synonymes: anticorps MGC68796, anticorps zgc:86678, anticorps wu:fd20e06, anticorps amisyn, anticorps hspc156, anticorps MGC88977, anticorps STXBP6, anticorps LOC100226852, anticorps BC024598, anticorps C85317, anticorps Amisyn, anticorps syntaxin binding protein 6 L homeolog, anticorps syntaxin binding protein 6 (amisyn), anticorps syntaxin binding protein 6, anticorps stxbp6.L, anticorps stxbp6, anticorps STXBP6, anticorps Stxbp6

Sujet:

Synonyms: Amisyn, HSPC156, STXB6_HUMAN, STXBP6, Syntaxin binding protein 6, Syntaxin-binding protein 6.

Background: Amisyn is a mostly cytosolic protein related to Tomosyn which plays an important role in SNARE complex assembly. Amisyn contains a v-SNARE coiled coil homology domain that binds to Syntaxin 1A and weakly to Syntaxin 4. Three isoforms exist for Amisyn. Isoform 1 is the full length protein, isoform 2 has a different amino acid sequence between residues 204-210 and isoform 3 is missing amino acids 1-102 and contains a different sequence for amino acids 103-150. Amisyn lacks a transmembrane domain and therefore is unable to assemble into a functional, membrane-anchored SNARE complex. This suggests that Amisyn may instead be acting to maintain SNARE conformation and facilitate the binding of VAMP-2. Amisyn can inhibit exocytosis independent of Syntaxin binding.