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KERA anticorps (AA 201-300) (AbBy Fluor® 488)

KERA Reactivité: Humain, Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 488
N° du produit ABIN1388992
  • Antigène Voir toutes KERA Anticorps
    KERA (Keratocan (KERA))
    Épitope
    • 14
    • 11
    • 10
    • 7
    • 2
    • 1
    • 1
    • 1
    AA 201-300
    Reactivité
    • 35
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 36
    • 1
    Lapin
    Clonalité
    • 37
    Polyclonal
    Conjugué
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KERA est conjugé à/à la AbBy Fluor® 488
    Application
    • 36
    • 17
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Keratocan
    Isotype
    IgG
    Top Product
    Discover our top product KERA Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    KERA (Keratocan (KERA))
    Autre désignation
    Keratocan (KERA Produits)
    Synonymes
    anticorps KERA, anticorps si:dkeyp-38g8.3, anticorps zgc:136259, anticorps CNA2, anticorps SLRR2B, anticorps keratocan, anticorps KERA, anticorps kera, anticorps Kera
    Sujet

    Synonyms: CNA2, KERA, KERA_HUMAN, Keratan sulfate proteoglycan keratocan, Keratocan, KTN, SLRR2B.

    Background: Small leucine-rich proteoglycans (SLRPs) such as Decorin, Biglycan, Fibromod-ulin, Keratocan, Lumican and Osteoglycin mediate extracellular matrix organization and are binding partners of TGF Beta. The Decorin core protein binds to growth factors, intercellular matrix molecules such as Fibronectin and Throm-bospondin, and to the Decorin endocytosis receptor. Fibromodulin is a collagen-binding keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. Keratocan (KTN) develops corneal transparency and maintains the stromal matrix structure. Keratocan is a secreted protein in the extracellular matrix that binds to keratan sulfate chains. Keratocan is mainly detected in the cornea, but can also be expressed in trachea, intestine, ovary, lung and skeletal muscle. Defects in the gene encoding for Keratocan can cause cornea plana 2 (CNA2), an autosomal recessive disorder where the forward convex curvature of the cornea is flattened.

    Pathways
    Glycosaminoglycan Metabolic Process
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