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Netrin 3 anticorps (AA 401-500) (AbBy Fluor® 555)

Ntn3 Reactivité: Humain, Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 555
N° du produit ABIN1389023
  • Antigène Voir toutes Netrin 3 (Ntn3) Anticorps
    Netrin 3 (Ntn3)
    Épitope
    • 14
    • 9
    • 9
    • 7
    • 1
    • 1
    AA 401-500
    Reactivité
    • 32
    • 15
    • 1
    Humain, Rat
    Hôte
    • 32
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Netrin 3 est conjugé à/à la AbBy Fluor® 555
    Application
    • 32
    • 15
    • 12
    • 12
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Rat
    Homologie
    Mouse,Dog,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human NTN3/Netrin-3
    Isotype
    IgG
    Top Product
    Discover our top product Ntn3 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Netrin 3 (Ntn3)
    Autre désignation
    NTN3/Netrin-3 (Ntn3 Produits)
    Synonymes
    anticorps NTN1, anticorps NTN2L, anticorps Ntn2l, anticorps netrin 3, anticorps netrin 1, anticorps NTN3, anticorps Ntn3
    Sujet

    Synonyms: NET3_HUMAN, Netrin-2-like protein, Netrin-3, NTN2L, NTN3.

    Background: Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins as the cells are repelled, rather than attracted, by the netrin gradient. Neogenin serves as the primary guidance receptor for netrin-3. Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, and, like netrin-1, they can either attract or repel commissural axons at a distance. Netrin-3 proteins are associated with the axon fibers projecting from motor neurons and from neurons within sympathetic and sensory ganglia, suggesting that netrin-3 may be involved in pathfinding and fasciculation of axon projection. Neogenin serves as the primary guidance receptor for netrin-3. During peripheral nerve development, high netrin-3 expression has been detected in mesenchymal cells, sensory ganglia and muscles. In humans, the gene encoding for the netrin-3 protein is localized to chromosome 16p13.3.

    Pathways
    Regulation of Muscle Cell Differentiation
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