DOK6 anticorps (AA 1-100) (AbBy Fluor® 647)
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- Antigène Voir toutes DOK6 Anticorps
- DOK6 (Docking Protein 6 (DOK6))
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Épitope
- AA 1-100
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DOK6 est conjugé à/à la AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human DOK6
- Isotype
- IgG
- Top Product
- Discover our top product DOK6 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- DOK6 (Docking Protein 6 (DOK6))
- Autre désignation
- DOK6 (DOK6 Produits)
- Synonymes
- anticorps DOK5L, anticorps HsT3226, anticorps Dok-6, anticorps RGD1564376, anticorps docking protein 6, anticorps DOK6, anticorps Dok6
- Sujet
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Synonyms: Docking protein 5, Docking protein 5 like, Docking protein 6, DOK 6, DOK6, DOK-6, DOK5, DOK 5, DOK-5, DOK5L, Downstream of tyrosine kinase 6, HsT3226, MGC20785, Protein dok 5, DOK6_HUMAN.
Background: The downstream of kinase family (Dok-1-7) are members of a class of docking? proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.
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