PCDHB12 anticorps (AA 121-220) (AbBy Fluor® 488)

N° du produit ABIN1389586

Détail du produit anti-PCDHB12 anticorps (AbBy Fluor® 488)

Antigène: PCDHB12 (Protocadherin beta 12 (PCDHB12))

Épitope: AA 121-220

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHB12 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PCDHB12

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PCDHB12

Antigène: PCDHB12 (Protocadherin beta 12 (PCDHB12))

Autre désignation: PCDHB12 (PCDHB12 Produits)

Synonymes: anticorps PCDH-BETA12, anticorps Pcdh3, anticorps Pcdhb5F, anticorps PcdhbL, anticorps PCDHB12, anticorps PCDHB10, anticorps PCDHB13, anticorps protocadherin beta 12, anticorps protocadherin beta-12, anticorps PCDHB12, anticorps Pcdhb12, anticorps LOC515337, anticorps LOC100452074

Sujet:

Synonyms: PCDH beta12, PCDHB 12, PCDHB12, PCDBC_HUMAN.

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB12 (Protocadherin beta 12) is a 795 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB12) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB12 is a single-pass type I membrane protein that contains six cadherin domains. PCDHB12 may participate in the establishment and maintenance of specific neuronal connections in the brain.