RASSF5 anticorps (AA 321-418) (AbBy Fluor® 350)
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- Antigène Voir toutes RASSF5 Anticorps
- RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))
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Épitope
- AA 321-418
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RASSF5 est conjugé à/à la AbBy Fluor® 350
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Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human RASSF5
- Isotype
- IgG
- Top Product
- Discover our top product RASSF5 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))
- Autre désignation
- RASSF5 (RASSF5 Produits)
- Synonymes
- anticorps Maxp1, anticorps NORE1, anticorps NORE1A, anticorps NORE1B, anticorps RAPL, anticorps RASSF3, anticorps 1300019G20Rik, anticorps AU042887, anticorps Nore1, anticorps Nore1A, anticorps Nore1B, anticorps Rapl, anticorps Ras association domain family member 5, anticorps Ras association (RalGDS/AF-6) domain family member 5, anticorps RASSF5, anticorps Rassf5
- Sujet
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Synonyms: RAPL, Maxp1, NORE1, NORE1A, NORE1B, RASSF3, Ras association domain-containing protein 5, New ras effector 1, Regulator for cell adhesion and polarization enriched in lymphoid tissues, RASSF5
Background: Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.
- ID gène
- 83593
- UniProt
- Q8WWW0
- Pathways
- TCR Signaling
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