GRAF anticorps (AA 1-100) (AbBy Fluor® 647)
-
- Antigène Voir toutes GRAF (ARHGAP26) Anticorps
- GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
-
Épitope
- AA 1-100
- Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp GRAF est conjugé à/à la AbBy Fluor® 647
-
Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog,Cow,Sheep,Pig,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human GRAF1
- Isotype
- IgG
- Top Product
- Discover our top product ARHGAP26 Anticorps primaire
-
-
- Indications d'application
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
- Autre désignation
- GRAF1 (ARHGAP26 Produits)
- Synonymes
- anticorps ARHGAP26, anticorps GRAF, anticorps GRAF1, anticorps OPHN1L, anticorps OPHN1L1, anticorps 1810044B20Rik, anticorps 2610010G17Rik, anticorps 4933432P15Rik, anticorps AI853435, anticorps mKIAA0621, anticorps Rho GTPase activating protein 26, anticorps ARHGAP26, anticorps Arhgap26
- Sujet
-
Synonyms: arhgap 26, ARHGAP26, FLJ42530, GRAF, GRAF1, GTPase regulator associated with focal adhesion kinase, GTPase regulator associated with focal adhesion kinase pp125FAK, KIAA0621, oligophrenin 1 like protein, Oligophrenin-1-like protein, oligophrenin1like protein, OPHN1L, OPHN1L1, RHG26_HUMAN, Rho GTPase activating protein 26, Rho GTPase activating protein26, Rho GTPase-activating protein 26, Rho-type GTPase-activating protein 26.
Background: Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.
-