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CCT2 anticorps (AA 131-230) (Biotin)

CCT2 Reactivité: Humain, Souris WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1390255
  • Antigène Voir toutes CCT2 Anticorps
    CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))
    Épitope
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 131-230
    Reactivité
    • 53
    • 39
    • 23
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 44
    • 8
    • 1
    Lapin
    Clonalité
    • 43
    • 10
    Polyclonal
    Conjugué
    • 27
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CCT2 est conjugé à/à la Biotin
    Application
    • 39
    • 13
    • 13
    • 9
    • 7
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CCT2/TCP1 beta
    Isotype
    IgG
    Top Product
    Discover our top product CCT2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))
    Autre désignation
    CCT2/TCP1 beta (CCT2 Produits)
    Synonymes
    anticorps fa26a01, anticorps fc58a11, anticorps CHUNP6883, anticorps wu:fa26a01, anticorps wu:fc58a11, anticorps cct2, anticorps MGC89448, anticorps CCT2, anticorps 99D8.1, anticorps CCT-beta, anticorps CCTB, anticorps PRO1633, anticorps TCP-1-beta, anticorps Cctb, anticorps chaperonin containing TCP1 subunit 2, anticorps chaperonin containing TCP1, subunit 2 (beta), anticorps chaperonin containing Tcp1, subunit 2 (beta), anticorps T-complex protein 1 subunit beta, anticorps CCT2, anticorps cct2, anticorps Cct2, anticorps cct-2
    Sujet

    Synonyms: CCT 2, CCT beta, CCT-beta, CCT-2, CCTB, Chaperonin containing t complex polypeptide 1 beta subunit, Chaperonin containing t complex polypeptide 1 subunit 2, Chaperonin containing TCP1 subunit 2, Chaperonin containing TCP1 subunit 2 beta, CTP:phosphocholine cytidylyltransferase 2, MGC142074, MGC142076, MGC94480, PRO1633, T complex protein 1 beta subunit, T complex protein 1 subunit beta, T-complex protein 1 subunit beta, TCP 1 beta, TCP-1-beta, TCPB_HUMAN, 99D8.1.

    Background: CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1). Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15 % of newly synthesized eukaryotic proteins (2). CCT2 is the _-subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress. This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3). CCT subunit levels also change throughout the cell cycle, with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4). Each CCT subunit is thought to perform a specific function during protein folding and assembly (5), CCT2 exhibits both actin and tubulin binding activities (6,3) but the exact molecular function on this subunit remains uncertain.

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