Membralin anticorps (AA 161-260) (AbBy Fluor® 350)

N° du produit ABIN1390581

Détail du produit anti-Membralin anticorps (AbBy Fluor® 350)

Antigène: Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

Épitope: AA 161-260

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Membralin est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Poisson zèbre (Danio rerio)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Membralin

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Membralin

Antigène: Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

Autre désignation: Membralin/C19orf6 (TMEM259 Produits)

Synonymes: anticorps ASBABP1, anticorps C19orf6, anticorps MBRL, anticorps MEMBRALIN, anticorps R32184_3, anticorps C28H19orf6, anticorps c19orf6, anticorps AC087114.7gm12, anticorps AC087114.7gm2, anticorps ORF61, anticorps mFLJ00277, anticorps Mbrl, anticorps RGD1311136, anticorps transmembrane protein 259, anticorps transmembrane protein 259 L homeolog, anticorps TMEM259, anticorps tmem259.L, anticorps Tmem259

Sujet:

Synonyms: ASBABP1, C19orf6, MGC4022, R32184_3, aspecic BCL2 ARE-binding protein 1, C19orf6, chromosome 19 open reading frame 6, MBRL, MBRL_HUMAN.

Background: The gene encoding human Membralin, C19orf6, localizes to chromosome 19p13.3. It contains 11 exons, which encode at least two splice variants in human cancer. Membralin is a multi-pass membrane protein and exists either as a long or short form. The long form of Membralin comprises all 11 exons, while the short form contains all exons except exon 10. Expression of different Membralin isoforms depends on tissue type. The long form is expressed in ovarian and colorectal carcinomas, whereas the short form is expressed in breast or pancreatic carcinomas. Because Membralin expression in ovarian carcinomas is highest in serous carcinomas as compared to surface epithelium carcinomas, expression of Membralin may be useful as a novel tumor-associated marker in ovarian serous carcinomas.