SV2B anticorps (AA 401-500) (AbBy Fluor® 488)

N° du produit ABIN1390840

Détail du produit anti-SV2B anticorps (AbBy Fluor® 488)

Antigène: SV2B (Synaptic Vesicle Glycoprotein 2B (SV2B))

Épitope: AA 401-500

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SV2B est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SV2B

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SV2B

Antigène: SV2B (Synaptic Vesicle Glycoprotein 2B (SV2B))

Autre désignation: SV2B (SV2B Produits)

Synonymes: anticorps SV2B, anticorps A830038F04Rik, anticorps AI850768, anticorps mKIAA0735, anticorps HsT19680, anticorps synaptic vesicle glycoprotein 2B, anticorps synaptic vesicle glycoprotein 2 b, anticorps synaptic vesicle glycoprotein 2b, anticorps SV2B, anticorps CpipJ_CPIJ009611, anticorps Sv2b

Sujet:

Synonyms: Synaptic vesicle protein 2B, SV2B_HUMAN.

Background: In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.

ID gène: 9899