SV2C anticorps (AA 451-550) (Biotin)

N° du produit ABIN1390849

Détail du produit anti-SV2C anticorps (Biotin)

Antigène: SV2C (Synaptic Vesicle Glycoprotein 2C (SV2C))

Épitope: AA 451-550

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SV2C est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SV2C

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur SV2C

Antigène: SV2C (Synaptic Vesicle Glycoprotein 2C (SV2C))

Autre désignation: SV2C (SV2C Produits)

Synonymes: anticorps si:dkey-18p14.1, anticorps 4930527L09Rik, anticorps AI841971, anticorps synaptic vesicle glycoprotein 2C, anticorps synaptic vesicle glycoprotein 2c, anticorps SV2C, anticorps sv2c, anticorps CpipJ_CPIJ005417, anticorps Sv2c

Sujet:

Synonyms: Synaptic vesicle protein 2c, SV2C_HUMAN.

Background: In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.

ID gène: 22987