Utrophin anticorps (Biotin)
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- Antigène Voir toutes Utrophin (UTRN) Anticorps
- Utrophin (UTRN)
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Utrophin est conjugé à/à la Biotin
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Application
- ELISA
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Utrophin
- Isotype
- IgG
- Top Product
- Discover our top product UTRN Anticorps primaire
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- Indications d'application
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IHC-P: 1:100-500
Optimal working dilution should be determined by the investigator. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- Utrophin (UTRN)
- Autre désignation
- Utrophin (UTRN Produits)
- Synonymes
- anticorps drp, anticorps dmdl, anticorps drp1, anticorps DKFZp469A0710, anticorps DMDL, anticorps DRP, anticorps DRP1, anticorps AA589569, anticorps Dmdl, anticorps utrophin L homeolog, anticorps utrophin, anticorps utrn.L, anticorps UTRN, anticorps LOAG_03796, anticorps utrn, anticorps LOC100551145, anticorps Utrn
- Sujet
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Synonyms: DMDL, DRP 1, DRP, DRP-1, DRP1, Dystrophin like protein, Dystrophin related protein 1, Dystrophin related protein, Dystrophin-related protein 1, FLJ23678, UTRN, UTRO_HUMAN, Utrophin homologous to dystrophin, Utrophin
Background: Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.
- ID gène
- 7402
- Pathways
- Skeletal Muscle Fiber Development
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