NMUR2 anticorps (AA 181-230) (Biotin)

N° du produit ABIN1391179

Détail du produit anti-NMUR2 anticorps (Biotin)

Antigène: NMUR2 (Neuromedin U Receptor 2 (NMUR2))

Épitope: AA 181-230

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMUR2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NMUR2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur NMUR2

Antigène: NMUR2 (Neuromedin U Receptor 2 (NMUR2))

Autre désignation: NMUR2/GPR-FM4 (NMUR2 Produits)

Synonymes: anticorps NMUR2, anticorps NMSR2, anticorps FM-4, anticorps FM4, anticorps NMU-R2, anticorps NMU2R, anticorps TGR-1, anticorps TGR1, anticorps Nmu2r, anticorps neuromedin U receptor 2, anticorps NMUR2, anticorps Nmur2

Sujet:

Synonyms: FM4, G protein coupled receptor FM 4, G protein coupled receptor TGR 1, G-protein coupled receptor FM-4, G-protein coupled receptor TGR-1, Neuromedin U receptor 2, Neuromedin-U receptor 2, NMU R2, NMU-R2, NMU2R, NMUR2, NMUR2_HUMAN, TGR1

Background: Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It?s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues.

ID gène: 56923

UniProt: Q9GZQ4

Pathways: Feeding Behaviour