ABLIM1 anticorps (AA 681-778) (AbBy Fluor® 647)
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- Antigène Voir toutes ABLIM1 Anticorps
- ABLIM1 (Actin Binding LIM Protein 1 (ABLIM1))
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Épitope
- AA 681-778
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ABLIM1 est conjugé à/à la AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human ABLIM1
- Isotype
- IgG
- Top Product
- Discover our top product ABLIM1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ABLIM1 (Actin Binding LIM Protein 1 (ABLIM1))
- Autre désignation
- ABLIM1 (ABLIM1 Produits)
- Synonymes
- anticorps ABLIM1, anticorps 2210411C18Rik, anticorps 2610209L21Rik, anticorps 4833406P10Rik, anticorps 9330196J19Rik, anticorps AV079770, anticorps AW060987, anticorps AW215784, anticorps Limab1, anticorps abLIM-L, anticorps abLIM-M, anticorps abLIM-S, anticorps mKIAA0059, anticorps ablim1, anticorps zgc:172321, anticorps RGD1565768, anticorps ABLIM, anticorps LIMAB1, anticorps LIMATIN, anticorps abLIM-1, anticorps si:dkeyp-84e12.1, anticorps zgc:112954, anticorps actin binding LIM protein 1, anticorps actin-binding LIM protein 1, anticorps actin binding LIM protein 1a, anticorps actin binding LIM protein 1b, anticorps ABLIM1, anticorps Ablim1, anticorps ablim1a, anticorps ablim1b
- Sujet
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Synonyms: ABLIM 1, ABLIM, abLIM-1, ABLIM-L, ABLIM-M, ABLIM-S, ABLIM1, ABLM1_HUMAN, Actin binding double zinc finger protein, Actin binding LIM protein 1, Actin binding LIM protein family member 1, Actin-binding double zinc finger protein, Actin-binding double zinc finger protein, Actin-binding LIM protein 1, Actin-binding LIM protein family member 1, DKFZp781D0148, FLJ14564, KIAA0059, LIM actin binding protein 1, LIMAB 1, LIMAB1, Limatin, RGD1565768, RP11-317F20.1.
Background: The C. elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors. The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, also designated Limatin). The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.
- ID gène
- 3983
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