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NGEF anticorps (AA 451-550) (Biotin)

NGEF Reactivité: Souris, Rat WB, ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1391395
  • Antigène Voir toutes NGEF Anticorps
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    Épitope
    • 15
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-550
    Reactivité
    • 40
    • 40
    • 34
    • 3
    • 3
    • 3
    • 3
    Souris, Rat
    Hôte
    • 47
    • 1
    Lapin
    Clonalité
    • 47
    • 1
    Polyclonal
    Conjugué
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NGEF est conjugé à/à la Biotin
    Application
    • 38
    • 26
    • 26
    • 10
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EPHEXIN
    Isotype
    IgG
    Top Product
    Discover our top product NGEF Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    Autre désignation
    Ephexin-1/EPHEXIN (NGEF Produits)
    Synonymes
    anticorps Ephexin-1, anticorps ARHGEF27, anticorps EPHEXIN, anticorps Tims2, anticorps ephexin, anticorps Besh3, anticorps ephexin-1, anticorps neuronal guanine nucleotide exchange factor, anticorps NGEF, anticorps Ngef
    Sujet

    Synonyms: EPHEXIN, ARHGEF27, Ephexin-1, Eph-interacting exchange protein, Neuronal guanine nucleotide exchange factor, NGEF

    Background: Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).

    ID gène
    25791
    UniProt
    Q8N5V2
    Pathways
    Neurotrophin Signaling Pathway
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