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ATRNL1 anticorps (AA 501-600) (AbBy Fluor® 488)

ATRNL1 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 488
N° du produit ABIN1391656
  • Antigène Voir toutes ATRNL1 Anticorps
    ATRNL1 (Attractin-Like 1 (ATRNL1))
    Épitope
    • 14
    • 1
    AA 501-600
    Reactivité
    • 17
    • 2
    Humain
    Hôte
    • 17
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATRNL1 est conjugé à/à la AbBy Fluor® 488
    Application
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ATRNL1
    Isotype
    IgG
    Top Product
    Discover our top product ATRNL1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ATRNL1 (Attractin-Like 1 (ATRNL1))
    Autre désignation
    ATRNL1 (ATRNL1 Produits)
    Synonymes
    anticorps AI504415, anticorps AW555641, anticorps Alp, anticorps Atrnl, anticorps Atrnlp, anticorps RGD1563485, anticorps ALP, anticorps bA338L11.1, anticorps bA454H24.1, anticorps attractin like 1, anticorps ATRNL1, anticorps Atrnl1
    Sujet

    Synonyms: ATRN1_HUMAN, ATRNL1, Attractin-like protein 1, KIAA0534.

    Background: ATRNL1 is a 1,379 amino acid single-pass type I membrane protein that may play a role in melanocortin signaling pathways that regulate energy homeostasis. The ATRNL1 protein contains a C-type lectin domain, a CUB domain, two EGF-like domains, six Kelch repeats, two laminin EGF-like domains and five PSI domains. ATRNL1 interacts with MC4-R in several regions known to be important in the regulation of energy homeostasis by melanocortins, such as the paraventricular nucleus of hypothalamus and the dorsal motor nucleus of the vagus. The ATRNL1 gene is conserved in dog, cow, mouse, rat, chicken, zebrafish and C. elegans, exists as two alternatively spliced isoforms and maps to human chromosome 10q25.3. Strong evidence of linkage to late-onset Alzheimer disease (LOAD) is linked to chromosome 10, which implicates a wide region and at least one disease-susceptibility locus.

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