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GALR3 anticorps (AA 1-100) (AbBy Fluor® 488)

GALR3 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 488
N° du produit ABIN1391800
  • Antigène Voir toutes GALR3 Anticorps
    GALR3 (Galanin Receptor 3 (GALR3))
    Épitope
    • 14
    • 12
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    • 45
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 45
    • 1
    Lapin
    Clonalité
    • 46
    Polyclonal
    Conjugué
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GALR3 est conjugé à/à la AbBy Fluor® 488
    Application
    • 34
    • 19
    • 12
    • 12
    • 9
    • 7
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GALR3
    Isotype
    IgG
    Top Product
    Discover our top product GALR3 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GALR3 (Galanin Receptor 3 (GALR3))
    Autre désignation
    GALR3 (GALR3 Produits)
    Synonymes
    anticorps GALR3, anticorps Galnr3, anticorps galanin receptor 3, anticorps GALR3, anticorps LOC100037699, anticorps Galr3
    Sujet

    Synonyms: GAL 3R, GAL R3, GAL3 R, GAL3-R, GAL3R, Galanin receptor 3, Galanin receptor-3, Galanin receptor family member 3, Galanin receptor type 3, GALN R3, GALNR 3, GALNR3, GALR 3, GALR-3, Galr3, GALR3_HUMAN.

    Background: GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.

    ID gène
    8484
    Pathways
    cAMP Metabolic Process, Feeding Behaviour
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