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RCAN3 anticorps (AA 151-241) (AbBy Fluor® 647)

RCAN3 Reactivité: Souris, Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 647
N° du produit ABIN1391886
  • Antigène Voir toutes RCAN3 Anticorps
    RCAN3 (RCAN Family Member 3 (RCAN3))
    Épitope
    • 15
    • 14
    • 9
    • 7
    • 6
    • 2
    • 1
    AA 151-241
    Reactivité
    • 40
    • 30
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 53
    • 1
    Lapin
    Clonalité
    • 53
    • 1
    Polyclonal
    Conjugué
    • 14
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RCAN3 est conjugé à/à la AbBy Fluor® 647
    Application
    • 40
    • 29
    • 21
    • 12
    • 12
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Calcipressin 3
    Isotype
    IgG
    Top Product
    Discover our top product RCAN3 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    RCAN3 (RCAN Family Member 3 (RCAN3))
    Autre désignation
    Calcipressin 3 (RCAN3 Produits)
    Synonymes
    anticorps DSCR1L2, anticorps rcn3, anticorps hrcn3, anticorps mcip3, anticorps dscr1l2, anticorps MGC145788, anticorps MCIP3, anticorps RCN3, anticorps hRCN3, anticorps Dscr1l2, anticorps AU041093, anticorps Csp3, anticorps wu:fc68f05, anticorps zgc:113155, anticorps zgc:91820, anticorps RCAN family member 3, anticorps calcipressin-3, anticorps regulator of calcineurin 3, anticorps RCAN3, anticorps Tsp_08182, anticorps rcan3, anticorps Rcan3
    Sujet

    Synonyms: Calcipressin-3, Down syndrome candidate region 1 like 2, regulator of calcineurin 3, Down syndrome candidate region 1 like protein 2, Down syndrome candidate region 1-like protein 2, Down syndrome critical region gene 1 like 2, DSCR1L2, hRCN3, MCIP3, Myocyte enriched calcineurin interacting protein 3, Myocyte-enriched calcineurin-interacting protein 3, RCAN family member 3, RCAN3, RCAN3_HUMAN, RCN3, Regulator of calcineurin 3.

    Background: Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events.

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