WWC1 anticorps (AA 351-450) (Biotin)

N° du produit ABIN1392055

Détail du produit anti-WWC1 anticorps (Biotin)

Antigène: WWC1 (WW and C2 Domain Containing 1 (WWC1))

Épitope: AA 351-450

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWC1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KIBRA

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur WWC1

Antigène: WWC1 (WW and C2 Domain Containing 1 (WWC1))

Autre désignation: KIBRA (WWC1 Produits)

Synonymes: anticorps CG12600, anticorps CG33967, anticorps CG7552, anticorps Dmel\\CG33967, anticorps Kibra, anticorps ORE-2, anticorps RE26350, anticorps kib, anticorps l(3)02404, anticorps l(3)j5C3, anticorps l(3)neo42, anticorps HBEBP3, anticorps HBEBP36, anticorps KIBRA, anticorps AA408228, anticorps AU017197, anticorps BC037006, anticorps mKIAA0869, anticorps CG33967 gene product from transcript CG33967-RB, anticorps WW and C2 domain containing 1, anticorps WW, C2 and coiled-coil domain containing 1, anticorps kibra, anticorps WWC1, anticorps Wwc1

Sujet:

Synonyms: KIBRA, HBEBP3, HBEBP36, MEMRYQTL, PPP1R168, Protein KIBRA, HBeAg-binding protein 3, Kidney and brain protein, WW domain-containing protein 1, WWC1, KIAA0869

Background: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.

ID gène: 23286

UniProt: Q8IX03