NAT8B anticorps (AA 221-227) (AbBy Fluor® 555)
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- Antigène Voir toutes NAT8B Anticorps
- NAT8B (N-Acetyltransferase 8B (GCN5-Related, Putative, Gene/pseudogene) (NAT8B))
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Épitope
- AA 221-227
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NAT8B est conjugé à/à la AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human NAT8B
- Isotype
- IgG
- Top Product
- Discover our top product NAT8B Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- NAT8B (N-Acetyltransferase 8B (GCN5-Related, Putative, Gene/pseudogene) (NAT8B))
- Autre désignation
- NAT8B (NAT8B Produits)
- Synonymes
- anticorps EG434057, anticorps Cml1, anticorps Cml6, anticorps Nat8, anticorps RGD621605, anticorps CML2, anticorps Hcml2, anticorps NAT8BP, anticorps N-acetyltransferase 8B, anticorps N-acetyltransferase 8B, pseudogene, anticorps N-acetyltransferase 8B (putative, gene/pseudogene), anticorps NAT8B, anticorps Nat8b-ps, anticorps Nat8b
- Sujet
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Synonyms: Camello like protein 2, Camello-like protein 2, CML2, Hcml2, N acetyltransferase 8B, NAT8B, NAT8B_HUMAN, NAT8BP, Probable N acetyltransferase 8B, Probable N-acetyltransferase 8B.
Background: Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-8B (N-acetyltransferase 8B), also known as CML2 (camello-like protein 2), is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation. A member of the camello family, NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13.2. The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, which leads to a stop codon and subsequently, a non-functional protein that is truncated in length. Similarly, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, as it causes the N-acetyltransferase to become disrupted. Human chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr syndrome.
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