NOMO1 anticorps (AA 701-800) (Biotin)

N° du produit ABIN1392205

Détail du produit anti-NOMO1 anticorps (Biotin)

Antigène: NOMO1 (NODAL Modulator 1 (NOMO1))

Épitope: AA 701-800

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOMO1 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NOMO1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur NOMO1

Antigène: NOMO1 (NODAL Modulator 1 (NOMO1))

Autre désignation: NOMO1 (NOMO1 Produits)

Synonymes: anticorps Nomo, anticorps PM5, anticorps D7Ertd156e, anticorps pM5, anticorps RGD1305240, anticorps NOMO2, anticorps DKFZP459L1733, anticorps Nomo1, anticorps NODAL modulator 1, anticorps nodal modulator 1, anticorps NOMO1, anticorps Nomo1, anticorps LOC515570, anticorps LOC714226, anticorps LOC100025365, anticorps LOC100174326, anticorps LOC100408200, anticorps LOC100464689, anticorps LOC100544619, anticorps LOC100626015, anticorps LOC454345, anticorps LOC489992, anticorps LOC100713781

Sujet:

Synonyms: Nodal modulator 1, NOMO 1, Nomo, NOMO1, NOMO1_HUMAN, PM5, pM5 protein, pM5 protein telomeric copy, NOMO1_HUMAN.

Background: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).