GLYT1 anticorps (AA 209-285) (Biotin)

N° du produit ABIN1392259

Détail du produit anti-GLYT1 anticorps (Biotin)

Antigène: GLYT1 (Glycine Transporter 1 (GLYT1))

Épitope: AA 209-285

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLYT1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Glyt1/SLC6A9

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GLYT1

Antigène: GLYT1 (Glycine Transporter 1 (GLYT1))

Autre désignation: Glyt1/SLC6A9 (GLYT1 Produits)

Synonymes: anticorps GLYT1, anticorps Glyt-1, anticorps Glyt1, anticorps GLYT-1, anticorps GLYT-1b, anticorps glyt1, anticorps slc6a9, anticorps glyT-1, anticorps glyT1, anticorps solute carrier family 6 member 9, anticorps solute carrier family 6 (neurotransmitter transporter, glycine), member 9, anticorps glycine transporter 1, anticorps SLC6A9, anticorps Slc6a9, anticorps glyt1, anticorps slc6a9

Sujet:

Synonyms: glycine transporter 1, Glyt 1, GlyT-1 antibodyGlyT1, SC6A9_HUMAN, SLC6A9, sodium and chloride dependent glycine transporter 1, Sodium- and chloride-dependent glycine transporter 1, Solute carrier family 6 member 9.

Background: Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).

ID gène: 6536

UniProt: P48067