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GLYT1 anticorps (AA 209-285) (Biotin)

GLYT1 Reactivité: Humain, Rat, Souris WB, ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1392259
  • Antigène Voir toutes GLYT1 Anticorps
    GLYT1 (Glycine Transporter 1 (GLYT1))
    Épitope
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 209-285
    Reactivité
    • 28
    • 28
    • 27
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 30
    Lapin
    Clonalité
    • 30
    Polyclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GLYT1 est conjugé à/à la Biotin
    Application
    • 24
    • 13
    • 13
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Glyt1/SLC6A9
    Isotype
    IgG
    Top Product
    Discover our top product GLYT1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    GLYT1 (Glycine Transporter 1 (GLYT1))
    Autre désignation
    Glyt1/SLC6A9 (GLYT1 Produits)
    Synonymes
    anticorps GLYT1, anticorps Glyt-1, anticorps Glyt1, anticorps GLYT-1, anticorps GLYT-1b, anticorps glyt1, anticorps slc6a9, anticorps glyT-1, anticorps glyT1, anticorps solute carrier family 6 member 9, anticorps solute carrier family 6 (neurotransmitter transporter, glycine), member 9, anticorps glycine transporter 1, anticorps SLC6A9, anticorps Slc6a9, anticorps glyt1, anticorps slc6a9
    Sujet

    Synonyms: glycine transporter 1, Glyt 1, GlyT-1 antibodyGlyT1, SC6A9_HUMAN, SLC6A9, sodium and chloride dependent glycine transporter 1, Sodium- and chloride-dependent glycine transporter 1, Solute carrier family 6 member 9.

    Background: Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).

    ID gène
    6536
    UniProt
    P48067
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