GSX1/GSH1 anticorps (AA 165-264) (Biotin)

N° du produit ABIN1392307

Détail du produit anti-GSX1/GSH1 anticorps (Biotin)

Antigène: GSX1/GSH1 (GSX1) (GS Homeobox 1 (GSX1))

Épitope: AA 165-264

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSX1/GSH1 est conjugé à/à la Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Gsh1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GSX1/GSH1

Antigène: GSX1/GSH1 (GSX1) (GS Homeobox 1 (GSX1))

Autre désignation: Gsh1 (GSX1 Produits)

Synonymes: anticorps gsh1, anticorps im:7138106, anticorps zgc:110817, anticorps GSH1, anticorps gsh-1, anticorps Gsh-1, anticorps Gsh1, anticorps GS homeobox 1, anticorps gsx1, anticorps GSX1, anticorps Gsx1

Sujet:

Synonyms: GS homeo box protein 1, GS homeobox 1, GSH1, GSX1, GSX1_HUMAN, Homeobox protein GSH-1 , Homeobox protein Gsh1.

Background: Growth hormone-releasing hormone (GHRH) stimulates secretion and synthesis of growth hormone (GH), causes somatotroph proliferation and may have direct actions in fetal/placental development, reproduction and immune function. It exerts its action through high-affinity GHRH receptors present in the anterior pituitary. GSH-1 (GS homeobox 1) is a 264 amino acid hypothalamic nuclear protein that functions as a transcription factor responsible for maintaining GHRH expression as well as playing an important role in pituitary development. Coexpression of CBP leads to significantly enhanced GSH-1-induced GHRH expression, which suggest that CBP may function as a co-activator. Knockdown of GSH-1 mRNA in mice causes a dwarf phenotype, which suggests that certain cases of familial dwarfism may be caused by a mutation of the GSH-1 gene.