PKD1L3 anticorps (AA 121-220) (AbBy Fluor® 647)
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- Antigène Voir toutes PKD1L3 Anticorps
- PKD1L3 (Polycystic Kidney Disease 1 Like 3 (PKD1L3))
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Épitope
- AA 121-220
- Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PKD1L3 est conjugé à/à la AbBy Fluor® 647
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human PKD1L3
- Isotype
- IgG
- Top Product
- Discover our top product PKD1L3 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PKD1L3 (Polycystic Kidney Disease 1 Like 3 (PKD1L3))
- Autre désignation
- PKD1L3 (PKD1L3 Produits)
- Synonymes
- anticorps polycystic kidney disease 1 like 3, anticorps polycystin 1 like 3, transient receptor potential channel interacting, anticorps Pkd1l3, anticorps PKD1L3
- Sujet
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Synonyms: PC1 like 3 protein, Polycystic kidney disease 1 like 3, Polycystic kidney disease protein 1 like 3, Polycystin 1 like 3, Polycystin 1L3,PK1L3_HUMAN.
Background: Polycystin-1L3 is a 1,732 amino acid multi-pass membrane protein that contains one PLAT domain, one GPS domain and one C-type lectin domain. Expressed at high levels in placenta and present at lower levels in lung and heart, Polycystin-1L3 is thought to function as an ion-channel regulator that may interact with Polycystin-L and play a role in heteromeric taste channels. The gene encoding Polycystin-1L3 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
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