SH3PXD2A anticorps (AA 261-360) (Biotin)

N° du produit ABIN1392499

Détail du produit anti-SH3PXD2A anticorps (Biotin)

Antigène: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Épitope: AA 261-360

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3PXD2A est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Rat

Homologie: Human,Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FISH

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur SH3PXD2A

Antigène: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Autre désignation: FISH (SH3PXD2A Produits)

Synonymes: anticorps FISH, anticorps SH3MD1, anticorps TKS5, anticorps 2310014D11Rik, anticorps AA589508, anticorps AI256723, anticorps AI413738, anticorps C230050L11, anticorps EG329070, anticorps Fish, anticorps Gm5098, anticorps Sh3md1, anticorps TSK5, anticorps Tks5, anticorps sh3pxd2a, anticorps si:dkey-82d4.2, anticorps SH3 and PX domains 2A, anticorps SH3 and PX domains 2Aa, anticorps SH3PXD2A, anticorps Sh3pxd2a, anticorps sh3pxd2aa

Sujet:

Synonyms: Adapter protein TKS5, Five SH3 domain-containing protein, SH3 and PX domain-containing protein 2A, SH3 multiple domains protein 1, Sh3md1, Sh3pxd2a, SPD2A_HUMAN, TKs5, Tyrosine kinase substrate with five SH3 domains.

Background: Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo, catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).