HAAO anticorps (AA 101-200) (AbBy Fluor® 488)

N° du produit ABIN1392790

Détail du produit anti-HAAO anticorps (AbBy Fluor® 488)

Antigène: HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))

Épitope: AA 101-200

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAAO est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HAAO

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HAAO

Antigène: HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))

Autre désignation: HAAO (HAAO Produits)

Synonymes: anticorps Afu2g17450, anticorps 0610007K21Rik, anticorps 0610012J07Rik, anticorps 3-HAO, anticorps 3-HAOxase, anticorps 3HAO, anticorps zgc:103585, anticorps HAO, anticorps 3-hydroxyanthranilate 3,4-dioxygenase, anticorps 3-hydroxyanthranilate 3,4-dioxygenase L homeolog, anticorps SPO1774, anticorps CNB05620, anticorps AFUA_2G17450, anticorps Bcep18194_C7641, anticorps Kfla_5491, anticorps Micau_4935, anticorps RBRH_03005, anticorps Krodi_1278, anticorps haao, anticorps HAAO, anticorps Haao, anticorps haao.L

Sujet:

Synonyms: 3 HAO,3 hydroxyanthranilate 3 4 dioxygenase,3 hydroxyanthranilate dioxygenase,3 hydroxyanthranilate oxygenase,3 hydroxyanthranilic acid dioxygenase,3-HAO,3-hydroxyanthranilate 3,3-hydroxyanthranilate 3,4-dioxygenase,3-hydroxyanthranilate oxygenase,3-hydroxyanthranilic acid dioxygenase,3HAO_HUMAN,4-dioxygenase,haao,HAD,HAO.

Background: The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe2+ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4.