AFF2 anticorps (AA 1-80) (Biotin)

N° du produit ABIN1392841

Détail du produit anti-AFF2 anticorps (Biotin)

Antigène: AFF2 (AF4/FMR2 Family, Member 2 (AFF2))

Épitope: AA 1-80

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFF2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human AFF2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur AFF2

Antigène: AFF2 (AF4/FMR2 Family, Member 2 (AFF2))

Autre désignation: FMR2/AFF2 (AFF2 Produits)

Synonymes: anticorps FMR2, anticorps FMR2P, anticorps FRAXE, anticorps MRX2, anticorps OX19, anticorps Fmr2, anticorps Ox19, anticorps Oxh, anticorps AF4/FMR2 family member 2, anticorps AF4/FMR2 family, member 2, anticorps AFF2, anticorps Aff2

Sujet:

Synonyms: AF4/FMR2 family member 2, AF4/FMR2 family, member 2, AFF2, AFF2_HUMAN, FMR2, FMR2P, Fragile X E mental retardation syndrome protein, fragile X mental retardation 2, Fragile X mental retardation 2 protein, fragile X mental retardation gene associated with FRAXE, FRAXE, mild or borderline mental retardation, MRX2, OX19, Protein FMR-2, Protein Ox19.

Background: FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family. Expressed in the brain, placenta and lung, FMR2 exists as two isoforms produced by alternative splicing. Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, an X-linked form of mental retardation. Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, compared to six to thirty-five copies of the GCC repeat in a normal individual. It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site.