DGCR6 anticorps (AA 112-180) (AbBy Fluor® 647)
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- Antigène Voir toutes DGCR6 Anticorps
- DGCR6 (DiGeorge Syndrome Critical Region Gene 6 (DGCR6))
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Épitope
- AA 112-180
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DGCR6 est conjugé à/à la AbBy Fluor® 647
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human DGCR6
- Isotype
- IgG
- Top Product
- Discover our top product DGCR6 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- DGCR6 (DiGeorge Syndrome Critical Region Gene 6 (DGCR6))
- Autre désignation
- DGCR6 (DGCR6 Produits)
- Synonymes
- anticorps AU044152, anticorps DGCR6, anticorps DKFZp459P114, anticorps DGCR6L, anticorps zgc:101841, anticorps DiGeorge syndrome critical region gene 6, anticorps protein DGCR6, anticorps DiGeorge syndrome critical region gene 6 S homeolog, anticorps DGCR6, anticorps Dgcr6, anticorps LOC458642, anticorps dgcr6.S, anticorps dgcr6
- Sujet
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Synonyms: DGCR 6, DGCR6 protein, DiGeorge syndrome critical region 6, DiGeorge syndrome critical region gene 6, DGCR6_HUMAN.
Background: Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome. DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22. Expressed ubiquitously with highest levels in heart, liver and skeletal muscle, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin ?1, both of which are involved in early tissue development. The gene encoding DGCR6, along with other DGCR genes, is deleted in DiGeorge syndrome, a developmental disorder characterized by improper facial, cardiac and palate formation. Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, as well as in Burkitt_ lymphoma and lymphocytes transformed by EBV. Due to a duplication of the ancestral DGCR6 locus, there are two functional, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22.
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