EBF2 anticorps (AA 331-400) (Biotin)

N° du produit ABIN1393045

Détail du produit anti-EBF2 anticorps (Biotin)

Antigène: EBF2 (Early B-Cell Factor 2 (EBF2))

Épitope: AA 331-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EBF2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EBF2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur EBF2

Antigène: EBF2 (Early B-Cell Factor 2 (EBF2))

Autre désignation: EBF2 (EBF2 Produits)

Synonymes: anticorps EBF2, anticorps Zcoe2, anticorps D14Ggc1e, anticorps EBF-2, anticorps Mmot1, anticorps O/E-3, anticorps OE-3, anticorps EBF-2-A, anticorps Xcoe-2, anticorps Xcoe2, anticorps Xebf-2, anticorps Xebf-2-A, anticorps Xebf2, anticorps coe2, anticorps coe2-a, anticorps ebf2, anticorps oe3, anticorps COE2, anticorps early B-cell factor 2, anticorps early B cell factor 2, anticorps early B-cell factor 2 S homeolog, anticorps EBF2, anticorps ebf2, anticorps Ebf2, anticorps ebf2.S

Sujet:

Synonyms: COE 2, COE2, Collier Olf and EBF 2, Early B cell factor 2, EBF 2, FLJ11500, Metencephalon mesencephalnon olfactory transcription factor 1, O/E 3, O/E3, OE 3, OE3, OLF 1/EBF like 3, Transcription factor COE2, COE2_HUMAN.

Background: Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.

ID gène: 64641

UniProt: Q9HAK2