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EN1 anticorps (AA 351-392) (AbBy Fluor® 350)

EN1 Reactivité: Humain, Souris, Rat WB, FACS, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 350
N° du produit ABIN1393065
  • Antigène Voir toutes EN1 Anticorps
    EN1 (Engrailed Homeobox 1 (EN1))
    Épitope
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 351-392
    Reactivité
    • 30
    • 19
    • 18
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 35
    • 1
    Lapin
    Clonalité
    • 34
    • 2
    Polyclonal
    Conjugué
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EN1 est conjugé à/à la AbBy Fluor® 350
    Application
    • 25
    • 13
    • 12
    • 12
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EN1/Engrailed 1
    Isotype
    IgG
    Top Product
    Discover our top product EN1 Anticorps primaire
  • Indications d'application
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    EN1 (Engrailed Homeobox 1 (EN1))
    Autre désignation
    EN1/Engrailed 1 (EN1 Produits)
    Synonymes
    anticorps EN1, anticorps En-1, anticorps Mo-en.1, anticorps ENG-1, anticorps en-1, anticorps en1, anticorps eng1, anticorps zgc:100771, anticorps en1-A, anticorps engrailed-1, anticorps xen1, anticorps Gg-En-1, anticorps en-3, anticorps engrailed, anticorps engrailed homeobox 1, anticorps engrailed 1, anticorps engrailed homeobox 1a, anticorps engrailed homeobox 1 S homeolog, anticorps EN1, anticorps En1, anticorps en1a, anticorps en1.S
    Sujet

    Synonyms: En 1, EN1, Engrailed 1, Engrailed, Engrailed homeobox 1, Engrailed homolog 1, HME1_HUMAN, Homeobox protein en-1, Homeobox protein engrailed 1, Homeobox protein engrailed-1, Hu-En-1, Mo-en.1.

    Background: The engrailed-1 gene, EN1, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homo-logs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expres-sion of a-synuclein, a gene that is genetically linked to Parkinson?s disease.

    ID gène
    2019
    UniProt
    Q05925
    Pathways
    Dopaminergic Neurogenesis
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